Removing the brakes on post-stroke plasticity drives recovery from the intact hemisphere and spinal cord.

نویسندگان

  • Gergely Silasi
  • Timothy H Murphy
چکیده

Chan EM, Young EJ, Ianzano L, Munteanu I, Zhao X, Christopoulos CC, et al. Mutations in NHLRC1 cause progressive myoclonus epilepsy. Nat Genet 2003; 35: 125–7. Criado O, Aguado C, Gayarre J, Duran-Trio L, Garcia-Cabrero AM, Vernia S, et al. Lafora bodies and neurological defects in malindeficient mice correlate with impaired autophagy. Hum Mol Genet 2012; 21: 1521–33. Gayarre J, Durán-Trı́o L, Criado Garcia O, Aguado C, López L, Crespo I, et al. The phosphatase activity of laforin is dispensible to rescue Epm2a-/mice from Lafora disease. Brain 2014Advance Access published on January 14. 2014, doi:10.1093/brain/awt353. Gentry MS, Dowen RH III, Worby CA, Mattoo S, Ecker JR, Dixon JE. The phosphatase laforin crosses evolutionary boundaries and links carbohydrate metabolism to neuronal disease. J Cell Biol 2007; 178: 477–88. Gentry MS, Worby CA, Dixon JE. Insights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin. Proc Natl Acad Sci USA 2005; 102: 8501–6. Lafora GR. Uber das vorkommen amyloider korperchen im innern der ganglienzellen: zugleich en beitrag zum stadium der amyloiden substanz im nervensystem. Virchows Arch Pathol Anat Physiol Klin Med 1911; 205: 295–303. Minassian BA, Lee JR, Herbrick JA, Huizenga J, Soder S, Mungall AJ, et al. Mutations in a gene encoding a novel protein tyrosine phosphatase cause progressive myoclonus epilepsy. Nat Genet 1998; 20: 171–4. Pederson BA, Turnbull J, Epp JR, Weaver SA, Zhao X, Pencea N, et al. Inhibiting glycogen synthesis prevents lafora disease in a mouse model. Ann Neurol 2014[Epub ahead of print]. Tagliabracci VS, Girard JM, Segvich D, Meyer C, Turnbull J, Zhao X, et al. Abnormal metabolism of glycogen phosphate as a cause for Lafora disease. J Biol Chem 2008; 283: 33816–25. Tiberia E, Turnbull J, Wang T, Ruggieri A, Zhao XC, Pencea N, et al. Increased laforin and laforin binding to glycogen underlie Lafora body formation in malin-deficient Lafora disease. J Biol Chem 2012; 287: 25650–9.

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عنوان ژورنال:
  • Brain : a journal of neurology

دوره 137 Pt 3  شماره 

صفحات  -

تاریخ انتشار 2014